Check out the Life list of "Famous Literary Drunks & Addicts." Here are a couple of my favorites:
Ernest Hemingway (1899 - 1961): Booze
Notorious for making fun of his fellow writers who sought relief from their own alcoholism (when Fitzgerald admitted that alcohol had bested him, Hemingway urged him to toss his "balls into the sea -- if you have any balls left"), Papa himself was an increasingly messy drunk. George Plimpton once famously observed that by the end, Hemingway's ruined liver protruded from his belly "like a long fat leech."
Hunter S. Thompson (1937 - 2005): Everything
"I wouldn't recommend sex, drugs, or insanity for everyone, but they've always worked for me."
Dr. Pauly hasnt made the list...yet.